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A single copy of these materials may be reprinted for noncommercial personal use only. WebMD does not provide medical advice, diagnosis or treatment. health information, we will treat all of that information as protected health Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. Am J Clin Nutr 1995;61:62-8. 2014 Jul;63(7):945-50. JAMA Pediatr. Advertising revenue supports our not-for-profit mission. Effects of flaxseed supplements on blood pressure: a systematic review and meta-analysis of controlled clinical trial. View abstract. Flaxseed might lower blood sugar levels. Pan A, Demark-Wahnefried W, Ye X, et al. Eur J Clin Nutr 2007;61:1423-8. Cancer Causes Control 2006;17:1253-61. Wang L, Chen J, Thompson LU. Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia. Demark-Wahnefried W, Price DT, Polascik TJ, et al. Obes Rve. Taking flaxseed along with medications that lower blood pressure might cause blood pressure to go too low. Plasma phytoestrogens and subsequent breast cancer risk. other information we have about you. Eur.J Clin.Nutr. those that alter your blood flow and bleeding, including: some nonsteroidal anti-inflammatory drugs, like ibuprofen and naproxen. However, it requires a steady dose of essential nutrients, which must come from food or supplements, in order to function at its best. Mani UV, Mani I, Biswas M, Kumar SN. The adequate intake (AI) for omega-3 fatty acids is 1.6 grams for men and 1.1 grams for women. Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil) Digoxin Licorice The herb licorice may lower warfarin levels and can add to digoxin's effects. Flaxseed oil might lower blood pressure. Answer: Method 1 of 2:Taking Flaxseed Oil It is important to ask your doctor about adding flaxseed oil to your diet, especially if you are taking certain medications. The effect of flaxseed powder on insulin resistance indices and blood pressure in prediabetic individuals: a randomized controlled clinical trial. Rheumatol Int 1995;14:231-4. Brand names: Flax Seed Oil, Flax Oil Eating flaxseed in muffins or other foods seems to increase, High cholesterol. (2014). Leon F, Rodriguez M, Cuevas M. Anaphylaxis to Linum. J Natl Cancer Inst 2007;99:475-86. Ramon JM, Bou R, Romea S, et al. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. Atherosclerosis 1998;136:367-75. Allergol Immunopathol (Madr) 2003;31:47-9. . Sadat Masjedi M, Mohammadi Pour P, Shokoohinia Y, Asgary S. Effects of Flaxseed on Blood Lipids in Healthy and Dyslipidemic Subjects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. What should I know regarding pregnancy, nursing and administering Flaxseed to children or the elderly. Medicinal use of this product has not been approved by the FDA. View abstract. Nutr Metab (Lond) 2021;18(1):91. Demark-Wahnefried W, Robertson CN, Walther PJ, et al. 2017 Sepl18(9):1096-1107. Drug class: Herbal products. Alvarez-Perea A, Alzate -Prez D, Doleo Maldonado A, Baeza ML. J Med Food. Am J Clin Nutr 2006;84:400-5. Chen J, Power KA, Mann J, et al. Saw palmetto Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin Clopidogrel Warfarin St. John's wort "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Flaxseed oil might lower blood pressure. Obes Facts 2022. Nutr J 2011;10:44. Flaxseed is used for constipation, diabetes, high cholesterol, obesity, and swelling of the kidneys in people with lupus. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Br J Nutr. (2015). View abstract. Eating flaxseeds can have gastrointestinal side effects and can significantly increase the number of bowel movements you have in a day. Complement Ther Med. Taking flaxseed along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Serraino M, Thompson LU. Wang C, Makela T, Hase T, et al. Haggans CJ, Hutchins AM, Olson BA, et al. How fast does psyllium work? Mayo Clinic does not endorse companies or products. View abstract. Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. Circulating enterolactone and risk of endometrial cancer. The grapefruit causes larger amounts of the medication to stay in your body for a longer period of time, explains Mayo Clinic nutritionist Katherine Zeratsky 3. Natural Medicines. Touillaud MS, Thiebaut AC, Fournier A, et al. The omega-3 supplement may increase your fasting blood sugar levels and decrease the effectiveness of your diabetes medication. Effects of flaxseed and flaxseed oil supplement on serum levels of inflammatory markers, metabolic parameters and severity of disease in patients with ulcerative colitis. Do not give any herbal/health supplement to a child without medical advice. 4. Kuijsten A, Arts IC, Hollman PC, et al. View abstract. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. J Med Food 2008;11:207-14. Select a condition to view a list of vitamins. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. People use flaxseed and flaxseed oil to reduce cholesterol and blood sugar and treat digestive conditions. View abstract. View abstract. What medications does flaxseed interfere with? the unsubscribe link in the e-mail. Cabbage - Sulconazole. Human metabolism of mammalian lignan precursors in raw and processed flaxseed. 2005 - 2023 WebMD LLC. While some studies support health claims, most are small, and more research is needed. View abstract. J Am Coll Nutr 2010;29(1):72-80. These medications may interact and cause very harmful effects. Fact Checked by Paul Bossung. There is some concern that it might interfere with the body's ability to absorb medications taken by mouth because it might sweep them out of the digestive tract too quickly. Discuss with your doctor the benefits of flaxseed oil for your health before trying it out. The authors of the article in the Journal of Food Science and Technology call flaxseed oil a functional food because of its potential health benefits. Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. View abstract. You can find flaxseed oil in oil form, in capsules, or even in enriched food products. View abstract. 1995;49(3):169-178. However, when taken in large amounts and with too little water, flaxseed can cause: Avoid use of flaxseed and flaxseed oil during pregnancy. (2008). Pharmacol Res. View abstract. View abstract. Because of the potential for flaxseed oil side effects and drug interactions, you should talk to your primary care provider before regularly supplementing your diet with the plant oil. To be as proactive as possible, consult your doctor about using flaxseed oil as a dietary supplement before you begin to use it. Sairanen U, Piirainen L, Nevala R, Korpela R. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Savas BB, Alparslan GB, Korkmaz C. Effect of flaxseed poultice compress application on pain and hand functions of patients with hand osteoarthritis. It may take 1 to 3 days before this medication starts working. Do not use this product without medical advice if you are breast-feeding a baby. The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Daily flaxseed consumption improves glycemic control in obese men and women with pre-diabetes: a randomized study. Yari Z, Cheraghpour M, Hekmatdoost A. Flaxseed and/or hesperidin supplementation in metabolic syndrome: an open-labeled randomized controlled trial. View abstract. Chan School of Public Health: "Omega-3 Fatty Acids: An Essential Contribution", National Institutes of Health National Center for Complementary and Integrative Health: "Flaxseed and Flaxseed Oil", Harvard Health Publishing: "Why Not Flaxseed Oil? Yes, several popular herbal supplements can impact the effectiveness of apixaban (Eliquis), rivaroxaban (Xarelto), betrixaban (Bevyxxa), and other anticoagulant drugs (blood-thinners) classified as direct factor Xa inhibitors. J Womens Health (Larchmt) 2008;17:355-66. Research on the use of flaxseed and flaxseed oil for specific conditions shows: When used in combination with daily exercise and a low cholesterol diet, flaxseed might help control cholesterol levels. Read More Created for people with ongoing healthcare needs but benefits everyone. There are three primary types of omega-3s, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Flaxseed interacts with 583 drugs . 2016 Jun;67(4):461-9. Flaxseed oil may be a good option for you. Avoid using flax together with other herbal/health supplements that can also affect blood-clotting. View abstract. Do not use more of this product than is recommended on the label. Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. To help you remember, take it at the same time(s) each day. Can increase. Lifestyle counseling and supplementation with flaxseed or walnuts influence the management of metabolic syndrome. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. Bacteria in the intestine convert some of the chemicals in flaxseed into lignans, which are thought to be responsible for many of the possible benefits of flaxseed. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. Sung MK, Lautens M, Thompson LU. The Mayo Clinic warns that using flaxseed oil with this blood thinner, or any other anticoagulant, may increase your risk of bleeding. View abstract. Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Chan School of Public Health, 17 Reasons Why You Probably Need More Omega-3s in Your Diet, National Center for Complementary and Integrative Health. Stop using flax and call your healthcare provider at once if you have: bloating, gas, stomach ache, constipation, diarrhea, and nausea. Cancer Causes Control 2000;11:679-85. This means that flaxseed can help improve digestion and lower cholesterol levels, while flaxseed oil does not have these effects. It is created by eHealthMe based on reports of 30 people who take . Moreover, the National Center for Biotechnology Information shared an article from the Division of Natural Products, which is a branch of the Food and Drug Administration, agreeing with the dangers that flaxseed can have on the . Cancer Epidemiol Biomarkers Prev 2000;9:719-25. View abstract. ", Kardiologia Polska: "Linseed Oil Increases HDL3 Cholesterol and Decreases Blood Pressure in Patients Diagnosed With Mild Hypercholesterolaemia", Phytotherapy Research: "A Comparison Between the Effects of Flaxseed Oil and Fish Oil Supplementation on Cardiovascular Health in Type 2 Diabetic Patients With Coronary Heart Disease: A Randomized, Double-Blinded, Placebo-Controlled Trial", U.S. National Library of Medicine: "Warfarin". Excess sodium disturbs the water. Plasma enterolignan concentrations and colorectal cancer risk in a nested case-control study. Flaxseed oil as a dietary supplement is not regulated by the U.S. Food and Drug Administration. 2015 Apr;145(4):758-65. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. 2005-2023 Healthline Media a Red Ventures Company. View abstract. Medically reviewed by Drugs.com on Jul 25, 2022. The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. You should stop consuming these seeds, if you notice any itching, swelling, redness, or hives. View abstract. Flaxseeds are high in potassium. 2013 Aug 1;167(8):708-13. Demark-Wahnefried W, Polascik TJ, George SL, et al. Avoid using flax together with other herbal/health supplements that can lower blood sugar, such as alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. Anticoagulant and anti-platelet drugs, herbs and supplements. View abstract. Toulabi T, Yarahmadi M, Goudarzi F, Ebrahimzadeh F, Momenizadeh A, Yarahmadi S. Effects of flaxseed on blood pressure, body mass index, and total cholesterol in hypertensive patients: A randomized clinical trial.